We determined periodontal, inflammatory and oxidative stress parameters-total reactive oxygen species (ROS), superoxide production, intracellular Ca 2+, mitochondrial membrane potential and superoxide dismutase (SOD) activity. All the subjects underwent non-surgical periodontal treatment. Forty-nine obese subjects with periodontitis were randomized by means of the minimization method and assigned to one of two groups, one of which underwent dietary therapy while the other did not. Methods: This was a pilot study with a before-and-after design. The secondary aim was to evaluate the effect of dietary therapy on both parameters of oxidative stress in leukocytes and leukocyte-endothelial cell interactions in an obese population. Aim: The primary objective of this pilot study was to evaluate the effect of non-surgical periodontal treatment.
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